How does the body fight with melanoma?

Here is a short (1min) and simplified video describing my project and some of the main results I have obtained so far. During my PhD, one of my research focus was to understand how melanoma can hide from the body’s defence mechanism, which is called the immune system. In my analyses,Read More

Understanding familial melanoma

  This is a brief video summarising my PhD project (ESR01) at the Wellcome Sanger Institute in Cambridge, UK.  It involves the sequencing and analysis of familial melanoma patients from across the world. To learn more, please read my blog post on the topic linked here. – Aravind Sankar (ESR01),Read More

Immune system: our new fingerprint

In recent years, a considerable number of melanoma patients have shown great tumour regression when treated with immunotherapy agents. However, there is still a long way to go, when it comes to effectively select the patients that will actually benefit from these. My PhD project at Lund University, focusesRead More

Studying genetic changes in melanoma

Have you ever wondered why some melanoma patients do better than others? How is this linked to changes in our genes? In this video, I will highlight part of my research as a PhD student at the Wellcome Sanger Institute in Cambridge, UK.   To learn more, check outRead More

Melanoma: win the battle against your resistance

In the past years, we have drastically improved treatments for melanoma-skin cancer patients. Nevertheless, tumor recurrence still remains an highly lethal matter of our concern.   I’m pursing my PhD project in the melanoma genomics lab-group of Göran Jönssön, where we are specifically working with melanoma cells invulnerable towards current effectiveRead More

Can we slow down skin cancer progression?

The progression from benign cells to melanoma is not fully understood. In addition to genetic alterations, some epigenetic mechanisms, the ones that do not involve DNA sequence, play a role in the development and evolution of melanoma. My PhD project aims to disclose the epigenetic features behind melanoma progression. WeRead More

Are my genes contributors to melanoma?

  Looking to learn more about genes as contributors to cancer development? This is a short clip about melanoma genetics and the PhD project I have been working on for the past 3 years as part of the MelGen European training network! I aim to understand how the riskRead More

Liquid biopsy for the assessment of metastatic melanoma

Liquid biopsy employs the analyses of circulating cell-free DNA (ctDNA). ctDNA can be found in the plasma, and it provides a non-invasive approach in the assessment of metastatic melanoma. Moreover, it allows for real-time monitoring of progression or response to therapies. ctDNA is a promising predictive biomarker, that hasRead More